GPR124 Antikörper (C-Term)

Produktnummer ABIN6990813

Dieses Anti-GPR124-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GPR124 in ELISA, WB und IHC (p). Geeignet für Human und Ratte.

Kurzübersicht für GPR124 Antikörper (C-Term) (ABIN6990813)

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR124 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GPR124 Antikörper

Bindungsspezifität: AA 1270-1320, C-Term

Aufreinigung: TEM5 Antibody is affinity chromatography purified via peptide column.

Immunogen: TEM5 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human TEM5. The immunogen is located within amino acids 1270 - 1320 of TEM5.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TEM5 antibody can be used for detection of TEM5 by Western blot at 2 and 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TEM5 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TEM5 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GPR124

Target: GPR124 (G Protein-Coupled Receptor 124 (GPR124))

Andere Bezeichnung: TEM5

Hintergrund: TEM5 Antibody: Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.

Gen-ID: 25960

UniProt: Q96PE1