DHX58 Antikörper (AA 200-250)

Produktnummer ABIN6990807

Dieses Anti-DHX58-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DHX58 in WB und ELISA. Geeignet für Human, Ratte und Maus.

Kurzübersicht für DHX58 Antikörper (AA 200-250) (ABIN6990807)

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX58 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DHX58 Antikörper

Bindungsspezifität: AA 200-250

Aufreinigung: LGP2 Antibody is affinity chromatography purified via peptide column.

Immunogen: LGP2 antibody was raised against a 11 amino acid synthetic peptide from near the center of human LGP2. The immunogen is located within amino acids 200 - 250 of LGP2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: LGP2 antibody can be used for detection of LGP2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: LGP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: LGP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DHX58

Target: DHX58 (DEXH (Asp-Glu-X-His) Box Polypeptide 58 (DHX58))

Andere Bezeichnung: LGP2

Hintergrund: LGP2 Antibody: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.

Gen-ID: 79132

UniProt: Q96C10