STEAP3 Antikörper (N-Term)

Produktnummer ABIN6990787

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STEAP3 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für STEAP3 Antikörper (N-Term) (ABIN6990787)

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STEAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-STEAP3 Antikörper

Bindungsspezifität: N-Term

Spezifität: This STEAP3 antibody does not cross-react with other STEAP proteins.

Aufreinigung: STEAP3 Antibody is affinity chromatography purified via peptide column.

Immunogen: STEAP3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human STEAP3. The immunogen is located within the first 50 amino acids of STEAP3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: STEAP3 antibody can be used for detection of STEAP3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: STEAP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: STEAP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu STEAP3

Target: STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))

Andere Bezeichnung: STEAP3

Hintergrund: STEAP3 Antibody: The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction, mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.

Molekulargewicht: Predicted: 55 kDa

Observed: 51 kDa

Gen-ID: 55240

UniProt: Q658P3

Pathways: Transition Metal Ion Homeostasis