CRLF2 Antikörper (AA 140-190)

Produktnummer ABIN6990750

Der Kaninchen Polyklonal anti-CRLF2 Antikörper (ABIN6990750) detektiert spezifisch CRLF2 in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für CRLF2 Antikörper (AA 140-190) (ABIN6990750)

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRLF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-CRLF2 Antikörper

Bindungsspezifität: AA 140-190

Aufreinigung: TSLP Receptor Antibody is affinity chromatography purified via peptide column.

Immunogen: TSLP receptor antibody was raised against a 21 amino acid synthetic peptide from near the center of mouse TSLP receptor. The immunogen is located within amino acids 140 - 190 of TSLP Receptor.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TSLP receptor antibody can be used for detection of TSLP receptor by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TSLP Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TSLP Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CRLF2

Target: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Andere Bezeichnung: TSLP Receptor

Hintergrund: TSLP Receptor Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells, co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. The approximately 75 kDa band seen in the immunoblot may be a post-translationally modified form of TSLP-R.

Gen-ID: 57914

NCBI Accession: NP_057924

UniProt: Q8CII9