SAMHD1 Antikörper (C-Term, pThr592)
Kurzübersicht für SAMHD1 Antikörper (C-Term, pThr592) (ABIN6990713)
Target
Alle SAMHD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term, pThr592
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Spezifität
- Phospho-SAMHD1 antibody will only detect the phosphorylated form of SAMHD1.
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Aufreinigung
- SAMHD1 (phospho Thr592) antibody is affinity chromatography purified via peptide column.
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Immunogen
- Anti-SAMHD1 (phospho Thr592) antibody was raised against a phosphorylated peptide corresponding to 18 amino acids near the carboxy terminus of human Phospho-SAMHD1 surrounding T592.
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Isotyp
- IgG
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Applikationshinweise
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WB: 0.05-1 μ,g/mL, IHC: 2.5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry and Immunofluorescence in human samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- SAMHD1 (phospho Thr592) antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- SAMHD1 (phospho Thr592) antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
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Andere Bezeichnung
- SAMHD1
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Hintergrund
- The SAM domain and HD domain 1 (SAMHD1) protein is upregulated in response to viral infection and is thought to play a role in innate immunity (1). SAMHD1 blocks the infection of HIV-1 and SIVdeltaVpx before reverse transcription in macrophages and dendritic cells (2), and this restriction is regulated by phosphorylation of SAMHD1 (3). Mutations in this gene have been associated with Aicardi-Goutieres syndrome (1).
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Molekulargewicht
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Predicted: 72kD
Observed: 72 kD kDa -
Gen-ID
- 25939
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NCBI Accession
- NP_056289
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UniProt
- Q9Y3Z3
Target
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