IL23 Antikörper (N-Term)

Produktnummer ABIN6990632

Der Kaninchen Polyklonal Anti-IL23-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, IL23 in Proben von Human und Maus zu detektieren.

Kurzübersicht für IL23 Antikörper (N-Term) (ABIN6990632)

Target: IL23 (Interleukin 23 (IL23))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-IL23 Antikörper

Bindungsspezifität: AA 40-90, N-Term

Aufreinigung: IL-23 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-IL-23 antibody was raised against a peptide corresponding to 17 amino acids near the amino terminus of human IL-23. The immunogen is located within amino acids 40 - 90 of IL-23.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.25-2 μ,g/mL, IF: 20 μ,g/mL, IHC: 2 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunofluorescence and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: IL-23 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: IL-23 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu IL23

Target: IL23 (Interleukin 23 (IL23))

Andere Bezeichnung: IL-23

Hintergrund: IL-23 Antibody: Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-α, from activated T cells, and can stimulate macrophages to produce TNF-α, and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.

Molekulargewicht: Predicted: 21kD

Observed: 22 kD kDa

Gen-ID: 51561

UniProt: Q9NPF7