Cadherin 13 Antikörper (N-Term)

Produktnummer ABIN6990560

Der Kaninchen Polyklonal anti-Cadherin 13 Antikörper wird verwendet zum Nachweis von Cadherin 13 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für Cadherin 13 Antikörper (N-Term) (ABIN6990560)

Target: Cadherin 13 (CDH13)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cadherin 13 Antikörper

Bindungsspezifität: AA 150-200, N-Term

Spezifität: At least two isoforms of T-cadherin are known to exist.

Aufreinigung: T-cadherin Antibody is affinity chromatography purified via peptide column.

Immunogen: T-cadherin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human T-cadherin. The immunogen is located within amino acids 150 - 200 of T-cadherin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: T-cadherin antibody can be used for the detection of T-cadherin by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for for immunohistochemistry starting at 5 μ,g/mL and immunocytochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: T-cadherin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: T-cadherin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Cadherin 13

Target: Cadherin 13 (CDH13)

Andere Bezeichnung: T-cadherin

Hintergrund: T-cadherin Antibody: T-cadherin was initially identified as cadherin-type cell adhesion molecule expressed in various neuronal populations in a temporally and spatially restricted pattern during axon growth. T-cadherin is an atypical member of the cadherin family because it does not possess the typical transmembrane and cytoplasmic domains but is instead anchored to the plasma membrane by glycosylphosphatidylinositol (GPI) linkage. T-cadherin may play a role in malignant tumor development as loss of the chromosome locus containing the T-cadherin gene correlates with the development of a variety of cancers. Recently it has been shown that T-cadherin can act as a receptor for hexameric and high-molecular weight forms of adiponectin, suggesting that T-cadherin may also play a role in metabolic regulation.

Molekulargewicht: Predicted: 78, 84 kDa

Observed: 85 kDa

Gen-ID: 956

NCBI Accession: NP_001248

UniProt: O75355

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization