ADIPOQ Antikörper (N-Term)

Produktnummer ABIN6990546

Dieses Anti-ADIPOQ-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ADIPOQ in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für ADIPOQ Antikörper (N-Term) (ABIN6990546)

Target: ADIPOQ (Adiponectin (ADIPOQ))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADIPOQ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ADIPOQ Antikörper

Bindungsspezifität: AA 40-90, N-Term

Aufreinigung: Adiponectin Antibody is affinity chromatography purified via peptide column.

Immunogen: Adiponectin antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human adiponectin. The immunogen is located within amino acids 40 - 90 of Adiponectin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Adiponectin antibody can be used for the detection of adiponectin by Western blot at 1 to 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 1 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Adiponectin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Adiponectin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ADIPOQ

Target: ADIPOQ (Adiponectin (ADIPOQ))

Andere Bezeichnung: Adiponectin

Hintergrund: Adiponectin Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike the CTRPs, which are expressed in a wide variety of tissues, adiponectin is reported to be expressed exclusively by differentiated adipocytes. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It is present in high levels in normal human plasma, but is reduced in obese subjects and often in those with increased insulin resistance and type 2 diabetes, suggesting that adiponectin may be a useful pharmacological target in various metabolic diseases.

Gen-ID: 9370

NCBI Accession: NP_004788

UniProt: Q15848