Claudin 4 Antikörper (C-Term)
Kurzübersicht für Claudin 4 Antikörper (C-Term) (ABIN6990468)
Target
Alle Claudin 4 (CLDN4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- At least four isoforms of CLAUDIN4 are known to exist, CLAUDIN4 antibody will detect all four isoforms
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Aufreinigung
- CLAUDIN4 Antibody is affinity chromatography purified via peptide column.
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Immunogen
- Anti-CLAUDIN4 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human CLAUDIN4. The immunogen is located within the last 50 amino acids of CLAUDIN4.
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Isotyp
- IgG
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Applikationshinweise
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WB: 0.5-2 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunofluorescence in human samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- CLAUDIN4 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- CLAUDIN4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Claudin 4 (CLDN4)
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Andere Bezeichnung
- CLAUDIN4
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Hintergrund
- CLAUDIN4 Antibody: CLAUDIN4 is an integral membrane protein belonging to the claudin family, a family of cellular adhesion molecules that are components of tight junctions. CLAUDIN4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. The CLAUDIN4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. CLAUDIN4 is frequently overexpressed in ovarian and other epithelial cancers.
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Molekulargewicht
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Predicted: 22kD
Observed: 22 kD kDa -
Gen-ID
- 1364
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NCBI Accession
- NP_001296
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UniProt
- O14493
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Pathways
- Hepatitis C
Target
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