PAK6 Antikörper (AA 260-310)

Produktnummer ABIN6990412

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAK6 in WB, ELISA, IF und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PAK6 Antikörper (AA 260-310) (ABIN6990412)

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-PAK6 Antikörper

Bindungsspezifität: AA 260-310

Spezifität: PAK6 antibody is predicted to not cross-react with other PAK family proteins.

Aufreinigung: PAK6 Antibody is affinity chromatography purified via peptide column.

Immunogen: PAK6 antibody was raised against a 13 amino acid synthetic peptide from near the center of human PAK6. The immunogen is located within amino acids 260 - 310 of PAK6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PAK6 antibody can be used for the detection of PAK6 by Western blot at 1 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PAK6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PAK6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PAK6

Target: PAK6 (P21-Activated Kinase 6 (PAK6))

Andere Bezeichnung: PAK6

Hintergrund: PAK6 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6. These proteins are not activated by Cdc42/Rac binding. PAK6 was initially identified as an androgen receptor in a yeast two hybrid screen and was found to be highly expressed in testis and prostate tissues. Later experiments have shown it to be activated by MAP kinase kinase 6 and p38 MAP kinase, suggesting that PAK6 may play a role in the cellular response to stress-related signals.

Molekulargewicht: Predicted: 75 kDa

Observed: 70 kDa

Gen-ID: 56924

NCBI Accession: NP_064553

UniProt: Q9NQU5