KLHL1 Antikörper (N-Term)

Produktnummer ABIN6990396

Dieses Anti-KLHL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KLHL1 in WB, ELISA und IHC (p). Geeignet für Human und Ratte.

Kurzübersicht für KLHL1 Antikörper (N-Term) (ABIN6990396)

Target: KLHL1 (Kelch-Like 1 (KLHL1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLHL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KLHL1 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: KLHL1 Antibody is immunoaffinity purified .

Immunogen: KLHL1 antibody was raised against a 14 amino acid synthetic peptide from near the amino-terminus of human KLHL1. The immunogen is located within the first 50 amino acids of KLHL1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: KLHL1 antibody can be used for the detection of KLHL1 by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: KLHL1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: KLHL1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu KLHL1

Target: KLHL1 (Kelch-Like 1 (KLHL1))

Andere Bezeichnung: KLHL1

Hintergrund: KLHL1 Antibody: The mammalian Kelch-like 1 (KLHL1) was initially discovered as a homolog to the Drosophila Kelch gene that is highly expressed in several brain tissues. The predicted protein domain structure of KLHL1 is characteristic of a number of proteins that bind actin, form dimers, and often act as actin-organizing proteins. Based on the presence of anti-sense RNA that spans the transcription and translation start sites as well as the first splice site of KLHL1 in brain tissue of individuals suffering from the neurodegenerative disorder spinocerebellar ataxia type 8 (SCA8), it has been suggested that KLHL1 is involved this disease and that regulation of KLHL1 protein may be affected by antisense RNA expression.

Molekulargewicht: Predicted: 82 kDa

Observed: 82 kDa

Gen-ID: 57626

UniProt: Q9NR64