PLIN3 Antikörper (N-Term)

Produktnummer ABIN6990373

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PLIN3 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für PLIN3 Antikörper (N-Term) (ABIN6990373)

Target: PLIN3 (Perilipin 3 (PLIN3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLIN3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PLIN3 Antikörper

Bindungsspezifität: AA 30-80, N-Term

Aufreinigung: TIP47 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-TIP47 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TIP47. The immunogen is located within amino acids 30 - 80 of TIP47.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-4 μ,g/mL, IHC-P: 2 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TIP47 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TIP47 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PLIN3

Target: PLIN3 (Perilipin 3 (PLIN3))

Andere Bezeichnung: TIP47

Hintergrund: TIP47 Antibody: Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.

Molekulargewicht: Predicted: 47kD and 46kD

Observed: 47kD and 46kD kDa

Gen-ID: 10226

UniProt: O60664