DC-SIGN/CD209 Antikörper (AA 250-300)

Produktnummer ABIN6990356

Der Kaninchen Polyklonal Anti-DC-SIGN/CD209-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, DC-SIGN/CD209 in Proben von Human zu detektieren.

Kurzübersicht für DC-SIGN/CD209 Antikörper (AA 250-300) (ABIN6990356)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DC-SIGN/CD209 Antikörper

Bindungsspezifität: AA 250-300

Aufreinigung: DC-SIGN Antibody is affinity chromatography purified via peptide column.

Immunogen: DC-SIGN antibody was raised against a synthetic peptide corresponding to 17 amino acids near the center of human DC-SIGN. The immunogen is located within amino acids 250 - 300 of DC-SIGN.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DC-SIGN antibody can be used for detection of DC-SIGN by Western blot at 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DC-SIGN Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DC-SIGN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: DC-SIGN

Hintergrund: DC-SIGN Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.

Molekulargewicht: Predicted: 44 kDa

Observed: 47 kDa

Gen-ID: 30835

UniProt: Q9NNX6