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STK17A Antikörper (N-Term)

Dieses Anti-STK17A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von STK17A in WB, ELISA, ICC und IF. Geeignet für Human.
Produktnummer ABIN6990303

Kurzübersicht für STK17A Antikörper (N-Term) (ABIN6990303)

Target

Alle STK17A Antikörper anzeigen
STK17A (serine/threonine Kinase 17a (STK17A))

Reaktivität

  • 59
  • 11
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 52
  • 8
Kaninchen

Klonalität

  • 53
  • 7
Polyklonal

Konjugat

  • 34
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser STK17A Antikörper ist unkonjugiert

Applikation

  • 37
  • 16
  • 13
  • 13
  • 7
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 9
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Spezifität

    No cross responses to DRAK2, DAP or ZIP kinases.

    Aufreinigung

    DRAK1 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    DRAK1 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DRAK1. The immunogen is located within the first 50 amino acids of DRAK1.

    Isotyp

    IgG
  • Applikationshinweise

    DRAK1 antibody can be used for detection of DRAK1 by Western blot at 1 μ,g/mL. An approximately 50 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    DRAK1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    DRAK1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    STK17A (serine/threonine Kinase 17a (STK17A))

    Andere Bezeichnung

    DRAK1

    Hintergrund

    DRAK1 Antibody: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK-1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 for DAP kinase-related apoptosis-inducing protein kinases. DRAKs contain an N-terminal kinase domain and a C-terminal regulation domain. Overexpression of DRAK1 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK1 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.

    Molekulargewicht

    50 kDa

    Gen-ID

    9263

    UniProt

    Q9UEE5
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