BAG4 Antikörper (N-Term)

Produktnummer ABIN6990302

Der Kaninchen Polyklonal Anti-BAG4-Antikörper wurde für WB, ELISA, ICC und IF validiert. Er ist geeignet, BAG4 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für BAG4 Antikörper (N-Term) (ABIN6990302)

Target: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-BAG4 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: SODD Antibody is Antibody is DEAE purified.

Immunogen: SODD antibody was raised against a peptide corresponding to amino acids near the amino terminus of human SODD. The immunogen is located within the first 50 amino acids of SODD.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SODD antibody can be used for detection of SODD by Western blot at 0.5 μ,g/mL. An approximately 60 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SODD Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SODD antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu BAG4

Target: BAG4 (BCL2-Associated Athanogene 4 (BAG4))

Andere Bezeichnung: SODD

Hintergrund: SODD Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNF-R1 and Fas. Several novel death receptors including DR3, DR4, DR5, and DR6 were recently identified. Cell death signal is transduced by death domain containing adapter molecules through the interaction with death domain of these death receptors. A novel TNF-R1 interacting protein was recently identified and designated SODD for silencer of death domains. SODD associates with the death domain of TNF-R1 and prevents constitutive activation of TNF-R1 signaling. TNF treatment releases SODD and permits adapter molecules such as TRADD recruiting to the active TNF-R1 complex, which activates TNF signaling pathways. SODD also interacts with DR3. SODD is ubiquitously expressed in human tissues and cell lines.

Molekulargewicht: 60 kDa

Gen-ID: 9530

UniProt: O95429

Pathways: Regulation of Actin Filament Polymerization