HAVCR1 Antikörper (AA 230-280)

Produktnummer ABIN6990296

Der Kaninchen Polyklonal anti-HAVCR1 Antikörper wird verwendet zum Nachweis von HAVCR1 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für HAVCR1 Antikörper (AA 230-280) (ABIN6990296)

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAVCR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HAVCR1 Antikörper

Bindungsspezifität: AA 230-280

Aufreinigung: TIM-1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-TIM-1 antibody was raised against a peptide corresponding to 16 amino acids near the center terminus of human TIM-1. The immunogen is located within amino acids 230 - 280 of TIM-1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-8 μ,g/mL

Antibody validated: Western Blot in human samples. All other applications and species not yet tested

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TIM-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TIM-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu HAVCR1

Target: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Andere Bezeichnung: TIM-1

Substanzklasse: Virus

Hintergrund: TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.

Molekulargewicht: Predicted: 44kD

Observed: 60kD (Post-modification: 4 N-linked glycosylation) kDa

Gen-ID: 26762

NCBI Accession: NP_036338

UniProt: Q96D42