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DNASE2 Antikörper (C-Term)

DNASE2 Reaktivität: Human ELISA, WB, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990276
  • Target Alle DNASE2 Antikörper anzeigen
    DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 33
    • 21
    • 2
    Human
    Wirt
    • 31
    • 3
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 14
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DNASE2 Antikörper ist unkonjugiert
    Applikation
    • 15
    • 14
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    DNase II Antibody is affinity chromatography purified via peptide column.
    Immunogen
    DNase II antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DNase II. The immunogen is located within the last 50 amino acids of DNase II.
    Isotyp
    IgG
    Top Product
    Discover our top product DNASE2 Primärantikörper
  • Applikationshinweise
    DNase II antibody can be used for detection of DNase II expression by Western blot at 0.5 μ,g/mL. An approximate 40 kDa band can be detected, which represents the pro-enzyme of DNase II. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    DNase II Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    DNase II antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))
    Andere Bezeichnung
    DNase II (DNASE2 Produkte)
    Synonyme
    CG7780 antikoerper, DNase antikoerper, DNase 1 antikoerper, DNase-1 antikoerper, DNase1 antikoerper, Dmel\\CG7780 antikoerper, dDNase II antikoerper, dnase2 antikoerper, MGC80103 antikoerper, DNASE2 antikoerper, LOC733868 antikoerper, fa92d01 antikoerper, wu:fa56d08 antikoerper, wu:fa92d01 antikoerper, DDBDRAFT_0188966 antikoerper, DDBDRAFT_0252883 antikoerper, DDB_0188966 antikoerper, DDB_0252883 antikoerper, Dnase2 antikoerper, DNASE2A antikoerper, DNL antikoerper, DNL2 antikoerper, Dnase2a antikoerper, Deoxyribonuclease II antikoerper, deoxyribonuclease II, lysosomal L homeolog antikoerper, deoxyribonuclease 2, lysosomal antikoerper, deoxyribonuclease II, lysosomal antikoerper, deoxyribonuclease II antikoerper, deoxyribonuclease II alpha antikoerper, DNaseII antikoerper, dnase2.L antikoerper, DNASE2 antikoerper, dnase2 antikoerper, Dnase2a antikoerper, Dnase2 antikoerper
    Hintergrund
    DNase II Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus. DNase II causes both chromatin condensation and DNA fragmentation. The genes encoding human, porcine, and murine DNase II have been cloned. The DNase II gene encodes a 40 kDa proenzyme. The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing. Overexpression of DNase II induces chromatin condensation. DNase II is ubiquitously expressed in human tissues.
    Molekulargewicht
    Aprox: 40 kDa
    Gen-ID
    1777
    UniProt
    O00115
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