DNASE2 Antikörper (C-Term)

Produktnummer ABIN6990276

Dieses Anti-DNASE2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DNASE2 in WB, ELISA, IHC (p) und IF. Geeignet für Human.

Kurzübersicht für DNASE2 Antikörper (C-Term) (ABIN6990276)

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-DNASE2 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: DNase II Antibody is affinity chromatography purified via peptide column.

Immunogen: DNase II antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DNase II. The immunogen is located within the last 50 amino acids of DNase II.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: DNase II antibody can be used for detection of DNase II expression by Western blot at 0.5 μ,g/mL. An approximate 40 kDa band can be detected, which represents the pro-enzyme of DNase II. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DNase II Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: DNase II antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu DNASE2

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Andere Bezeichnung: DNase II

Hintergrund: DNase II Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus. DNase II causes both chromatin condensation and DNA fragmentation. The genes encoding human, porcine, and murine DNase II have been cloned. The DNase II gene encodes a 40 kDa proenzyme. The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing. Overexpression of DNase II induces chromatin condensation. DNase II is ubiquitously expressed in human tissues.

Molekulargewicht: Aprox: 40 kDa

Gen-ID: 1777

UniProt: O00115