GFRA2 Antikörper (AA 360-410)

Produktnummer ABIN6990251

Produktdetails anti-GFRA2 Antikörper

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Bindungsspezifität: AA 360-410

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFRA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Aufreinigung: GFR alpha 2 Antibody is Ion exchange chromatography purified.

Immunogen: GFR alpha 2 antibody was raised against a 15 amino acid peptide near the center of human GFR alpha 2. The immunogen is located within amino acids 360 - 410 of GFR alpha 2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: GFR alpha 2 antibody can be used for detection of GFR alpha 2 by Western blot at 1 μ,g/mL. A 52 kDa band should be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: GFR alpha 2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: GFR alpha 2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu GFRA2

Target: GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

Andere Bezeichnung: GFR alpha 2 (GFRA2 Produkte)

Synonyme: GDNFRB antikoerper, NRTNR-ALPHA antikoerper, NTNRA antikoerper, RETL2 antikoerper, TRNR2 antikoerper, Retl2 antikoerper, NTNRALPHA antikoerper, ntnra antikoerper, retl2 antikoerper, trnr2 antikoerper, gdnfrb antikoerper, nrtnr-alpha antikoerper, gfra2 antikoerper, GDNF family receptor alpha 2 antikoerper, glial cell line derived neurotrophic factor family receptor alpha 2 antikoerper, GDNF family receptor alpha 2a antikoerper, GFRA2 antikoerper, Gfra2 antikoerper, gfra2 antikoerper, gfra2a antikoerper

Hintergrund: GFR alpha 2 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN. The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently. NTNRalpha was also termed GDNFRβ, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRα,-2 recently. GFRα,-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRα,-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.

Molekulargewicht: Predicted: 51 kDa

Observed: 52 kDa

Gen-ID: 2675

UniProt: O00451