BANF1 Antikörper (C-Term)

Produktnummer ABIN6990199

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BANF1 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BANF1 Antikörper (C-Term) (ABIN6990199)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BANF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-BANF1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: BANF1 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-BANF1 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy terminus of human BANF1. The immunogen is located within the last 50 amino acids of BANF1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 0.5-2 μ,g/mL, IF: 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: BANF1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: BANF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Andere Bezeichnung: BANF1

Hintergrund: BANF1 Antibody: Barrier-to-autointegration factor 1 (BANF1) is a conserved chromatin protein that non-specifically binds double-stranded DNA. BANF1 also interacts with a family of nuclear proteins that include LAP2, emerin, and MAN1. It is also a host cell component of retroviral pre-integration complexes (PICs), including that of HIV. BANF1 will bind to p55 Gag (the structural precursor of HIV-1 virions) as well as its cleaved product matrix. In addition to being a host cell component of the PIC, it is thought that BANF1 is also present at low levels in incoming virions, and thus might contribute to the assembly or activity of HIV-1 PICs through direct binding to matrix as well as DNA.

Molekulargewicht: Predicted: 10kD

Observed: 12 kD

Despite its predicted molecular weight, BANF1 often migrates at a higher size in SDS-PAGE. kDa

Gen-ID: 8815

UniProt: O75531