Hemagglutinin Antikörper

Produktnummer ABIN6990168

Dieses Anti-Hemagglutinin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Hemagglutinin in ELISA. Geeignet für Influenza A Virus H5N1.

Kurzübersicht für Hemagglutinin Antikörper (ABIN6990168)

Target: Hemagglutinin (HA)

Reaktivität: Influenza A Virus H5N1

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hemagglutinin Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 4F1F2

Produktdetails anti-Hemagglutinin Antikörper

Aufreinigung: Hemagglutinin Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Immunogen: A peptide corresponding to synthetic peptide corresponding to 14 amino acids in the middle of Hemagglutinin.

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: Hemagglutinin antibody can be used for the detection of the Hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μ,g/mL. Other applications are pending.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Hemagglutinin Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Hemagglutinin monoclonal antibody can be stored at -20°C, stable for one year.

Details zu Hemagglutinin

Target: Hemagglutinin (HA)

Andere Bezeichnung: Hemagglutinin

Substanzklasse: Influenza Protein

Hintergrund: Hemagglutinin Monoclonal Antibody: Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. The more recent virulent strain of H5N1 is now seen in Africa and Europe, as well as in southeast Asia. There is some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability. While efforts were made to use relatively conserved regions of the viral sequence as the antigen, the influenza virus genome has drifted somewhat from what was first reported. However, this antibody was able to recognize peptides derrived from viruses from Indonesian human patients infected in 2007.

UniProt: Q692M2