DC-SIGN/CD209 Antikörper

Produktnummer ABIN6990166

Dieses Maus Monoklonal-Antikörper erkennt spezifisch DC-SIGN/CD209 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DC-SIGN/CD209 Antikörper (ABIN6990166)

Target: DC-SIGN/CD209 (CD209) (CD209)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DC-SIGN/CD209 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 5D7

Produktdetails anti-DC-SIGN/CD209 Antikörper

Aufreinigung: DC-SIGN Monoclonal Antibody is immunoaffinity chromotography purified IgG.

Immunogen: A recombinant His-tagged protein fragment corresponding to the extracellular region of human DC-SIGN.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: DC-SIGN antibody can be used for detection of DC-SIGN in Western Blot at 1 - 2 μ,g/mL and in immunohistochemistry at 5 - 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: DC-SIGN Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: DC-SIGN monoclonal antibody can be stored at -20°C, stable for one year.

Details zu DC-SIGN/CD209

Target: DC-SIGN/CD209 (CD209) (CD209)

Andere Bezeichnung: DC-SIGN

Hintergrund: DC-SIGN Monoclonal Antibody: Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV-1, HIV-2 and SIV bind to DCs via DC-SIGN. ICAM-3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed DC-SIGNR, L-SIGN, and DC-SIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.

Molekulargewicht: Predicted: 44 kDa

Observed: 47 kDa

Gen-ID: 30835

UniProt: Q9NNX6