RHBDD1 Antikörper (C-Term)

Produktnummer ABIN6990162

Dieses Anti-RHBDD1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RHBDD1 in WB und ELISA. Geeignet für Human und Maus.

Kurzübersicht für RHBDD1 Antikörper (C-Term) (ABIN6990162)

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RHBDD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RHBDD1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: RHBDD1 Antibody is affinity chromatography purified via peptide column.

Immunogen: RHBDD1 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human RHBDD1. The immunogen is located within the last 50 amino acids of RHBDD1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RHBDD1 antibody can be used for detection of RHBDD1 by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human and mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RHBDD1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RHBDD1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RHBDD1

Target: RHBDD1 (Rhomboid Domain Containing 1 (RHBDD1))

Andere Bezeichnung: RHBDD1

Hintergrund: RHBDD1 Antibody: The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.

Gen-ID: 84236

UniProt: Q8TEB9