SARS-CoV-2 ORF6 Antikörper (C-Term)

Produktnummer ABIN6990152

Der Kaninchen Polyklonal Anti-SARS-CoV-2 ORF6-Antikörper wurde für ELISA validiert. Er ist geeignet, SARS-CoV-2 ORF6 in Proben von SARS Coronavirus-2 (SARS-CoV-2) zu detektieren.

Kurzübersicht für SARS-CoV-2 ORF6 Antikörper (C-Term) (ABIN6990152)

Target: SARS-CoV-2 ORF6

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARS-CoV-2 ORF6 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-SARS-CoV-2 ORF6 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: SARS-CoV-2 (COVID-19) ORF6 Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-SARS-CoV-2 (COVID-19) ORF6 antibody was raised against a peptide corresponding to 15 amino acids near the Carboxyl terminus of SARS-CoV-2 (COVID-19) ORF6 protein. The immunogen is located in the last 50 amino acids of SARS-CoV-2 (COVID-19) ORF6.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody validated: SARS-CoV-2 (COVID-19) ORF6 antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) ORF6 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SARS-CoV-2 (COVID-19) ORF6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SARS-CoV-2 ORF6

Target: SARS-CoV-2 ORF6

Substanzklasse: Viral Protein

Hintergrund: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. ORF6 disrupts cell nuclear import complex formation by tethering karyopherin alpha 2 and karyopherin beta 1 to the membrane. Retention of import factors at the ER/Golgi membrane leads to a loss of transport into the nucleus. Thereby it prevents STAT1 nuclear translocation in response to interferon signaling, thus blocking the expression of interferon stimulated genes (ISGs) that display multiple antiviral activities(3).

Gen-ID: 43740572