SARS-CoV-2 NSP14 Antikörper (AA 30-80)

Produktnummer ABIN6990151

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SARS-CoV-2 NSP14 in ELISA. Er zeigt eine Reaktivität gegenüber SARS Coronavirus-2 (SARS-CoV-2).

Kurzübersicht für SARS-CoV-2 NSP14 Antikörper (AA 30-80) (ABIN6990151)

Target: SARS-CoV-2 NSP14 (ExoN) (SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14) (ExoN))

Reaktivität: SARS Coronavirus-2 (SARS-CoV-2)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SARS-CoV-2 NSP14 Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-SARS-CoV-2 NSP14 Antikörper

Bindungsspezifität: AA 30-80

Aufreinigung: SARS-CoV-2 (COVID-19) NSP14 (ExoN) Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody was raised against a peptide corresponding to 14 amino acids near the center of SARS-CoV-2 (COVID-19) NSP14 (ExoN) protein. The immunogen is located between 30-80 amino acids of SARS-CoV-2 (COVID-19) NSP14 (ExoN).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody validated: SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SARS-CoV-2 (COVID-19) NSP14 (ExoN) Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu SARS-CoV-2 NSP14

Target: SARS-CoV-2 NSP14 (ExoN) (SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14) (ExoN))

Andere Bezeichnung: SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14)

Substanzklasse: Viral Protein

Hintergrund: Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP14 (ExoN) is an enzyme possessing two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity (3,4,5). It acts as a proofreading exoribonuclease for RNA replication, thereby lowering The sensitivity of the virus to RNA mutagens(6,7,8).

Gen-ID: 43740578

NCBI Accession: YP_009725309

UniProt: P0DTC1