Dieser Human Monoklonal Antikörper detektiert spezifisch SARS-CoV-2 Nucleocapsid in ELISA. Es zeigt Reaktivität gegenüber Proben von SARS Coronavirus-2 (SARS-CoV-2).
SARS-CoV-2 N
Reaktivität: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV)
ELISA, IF, Neut
Wirt: Human
Monoclonal
CR3018 (03-018)
unconjugated
Recombinant Antibody
Applikationshinweise
Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
5.0 mg/mL
Buffer
PBS, pH 7.4
Lagerung
-20 °C,4 °C
Informationen zur Lagerung
24 months from manufacturing at <-20 °C, 1 month, 2 to 8 °C under sterile conditions.
Target
SARS-CoV-2 Nucleocapsid (SARS-CoV-2 N)
Andere Bezeichnung
SARS-CoV-2 Nucleocapsid
Substanzklasse
Viral Protein
Hintergrund
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.