ARHGDIA Antikörper

Produktnummer ABIN6989737

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ARHGDIA in WB, IF und IF (cc). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ARHGDIA Antikörper (ABIN6989737)

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGDIA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-ARHGDIA Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-204 of human ARHGDIA (NP_001172006.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF(ICC) 1:50-200
IF()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Andere Bezeichnung: ARHGDIA

Hintergrund:

Synonyms: ARHGDIA,GDIA1,HEL-S-47e,NPHS8,RHOGDI,RHOGDI-1

Background: This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants.

Gen-ID: 396

UniProt: P52565

Pathways: Neurotrophin Signalübertragung