NCR1 Antikörper (AA 1-100)

Produktnummer ABIN6989555

Der Kaninchen Polyklonal anti-NCR1 Antikörper wird verwendet zum Nachweis von NCR1 in Proben von Human. Er wurde validiert für IF (p), IF (cc), IHC (p) und IHC (fro).

Kurzübersicht für NCR1 Antikörper (AA 1-100) (ABIN6989555)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCR1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NCR1 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: NCR1 Polyclonal Antibody

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NCR1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Andere Bezeichnung: NCR1

Hintergrund:

Synonyms: Natural killer cell p46-related protein, Natural cytotoxicity triggering receptor 1, NK-p46, NKp46, NK cell-activating receptor, Lymphocyte antigen 94 homolog, CD335, CD 335, LY94, NCTR1_HUMAN.

Background: The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines.

Gen-ID: 9437

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity