GPC1 Antikörper (AA 251-350)

Produktnummer ABIN6989325

Dieses Anti-GPC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GPC1 in ELISA, ICC, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Ratte.

Kurzübersicht für GPC1 Antikörper (AA 251-350) (ABIN6989325)

Target: GPC1 (Glypican 1 (GPC1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPC1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GPC1 Antikörper

Bindungsspezifität: AA 251-350

Kreuzreaktivität: Ratte

Homologie: Mouse,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Glypican 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GPC1

Target: GPC1 (Glypican 1 (GPC1))

Andere Bezeichnung: Glypican 1

Hintergrund:

Synonyms: FLJ38078, glypican, glypican1, GPC 1, Glypican-1, GPC1, Glypican proteoglycan 1, Gpc1, GPC1_HUMAN, Secreted glypican-1.

Background: Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparin sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Gen-ID: 14733

UniProt: Q9QZF2

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation