FERMT1 Antikörper (AA 601-677)
Kurzübersicht für FERMT1 Antikörper (AA 601-677) (ABIN6989195)
Target
Alle FERMT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 601-677
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Verwendungszweck
- Kindlin Polyclonal Antibody
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Kreuzreaktivität
- Human, Maus
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Homologie
- Rat,Dog,Sheep,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Kindlin
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- FERMT1 (Fermitin Family Member 1 (FERMT1))
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Andere Bezeichnung
- Kindlin
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Hintergrund
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Synonyms: C20orf42, Chromosome 20 open reading frame 42, DTGCU 2, DTGCU2, FERM1_HUMAN, Fermitin family homolog 1, Fermt1, FLJ20116, FLJ23423, KIND 1, KIND1, Kinderlin, Kindlerin, Kindlin 1, Kindlin syndrome protein, Kindlin-1, Kindlin1, Unc 112 related protein 1, Unc-112-related protein 1, Unc112 related protein, UNC112A, URP 1, URP1.
Background: Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
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Gen-ID
- 55612
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UniProt
- Q9BQL6
Target
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