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GIPC1 Antikörper (AA 171-270)

This anti-GIPC1 antibody (ABIN6989016) is a Rabbit Polyclonal antibody detecting GIPC1 in WB. Suitable for Mouse, Rat.
Produktnummer ABIN6989016

Kurzübersicht für GIPC1 Antikörper (AA 171-270) (ABIN6989016)

Target

Alle GIPC1 Antikörper anzeigen
GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

Reaktivität

  • 51
  • 20
  • 12
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 47
  • 4
  • 2
  • 1
Kaninchen

Klonalität

  • 53
  • 1
Polyklonal

Konjugat

  • 28
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GIPC1 Antikörper ist unkonjugiert

Applikation

  • 34
  • 25
  • 13
  • 13
  • 9
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 9
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-270

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Human,Cow,Sheep

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GIPC1?

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

    Andere Bezeichnung

    GIPC1

    Hintergrund

    Synonyms: C19ORF3, Chromosome 19 open reading frame 3, GIPC, GLUT1 C terminal binding protein, GLUT1CBP, IGF 1 receptor interacting protein 1, IIP 1, IIP1, NIP, PDZ domain-containing protein GIPC1, Regulator of G protein signalling 19 interacting protein 1, RGS19 interacting protein 1, RGS19IP1, SEMCAP, SYNECTIIN, Tax interaction protein 2, TIP 2, GIPC1_HUMAN.

    Background: GIPC, for GAIP interacting protein at the C terminus (also designated SEMCAP-1 or synectin), is a PDZ domain containing protein that interacts with RGS-GAIP, a GTPase-activating protein (GAP) for G(a i) subunits. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. PDZ domain-containing proteins are primarily localized to cell-cell junctions in epithelial cells and neurons where they coordinate the assembly of multiprotein complexes. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.

    Gen-ID

    10755

    UniProt

    O14908

    Pathways

    Dicarboxylic Acid Transport
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