HMGB3 Antikörper (HRP)

Produktnummer ABIN6987988

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HMGB3 in IHC (p). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für HMGB3 Antikörper (HRP) (ABIN6987988)

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGB3 Antikörper ist konjugiert mit HRP

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HMGB3 Antikörper (HRP)

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HMG4/HMGB3:1-100/200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HMGB3

Target: HMGB3 (High Mobility Group Box 3 (HMGB3))

Andere Bezeichnung: HMG4/HMGB3

Hintergrund:

Synonyms: High mobility group (nonhistone chromosomal) protein 4, High mobility group box 3, High mobility group protein 2a, High mobility group protein 4, High mobility group protein B3, High mobility group protein HMG4, HMG 4, HMG-2a, HMG-4, HMG2A, HMGB 3, HMGB3, HMGB3_HUMAN, MGC90319, Non histone chromosomal protein, Nonhistone chromosomal protein HMG4.

Background: HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291], Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008] Function : Binds preferentially single-stranded DNA and unwinds double stranded DNA. Similarity : Belongs to the HMGB family. Contains 2 HMG box DNA-binding domains.

Gen-ID: 3149

UniProt: O15347