RAP1A Antikörper (AA 1-100) (HRP)

Produktnummer ABIN6987853

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAP1A in WB. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für RAP1A Antikörper (AA 1-100) (HRP) (ABIN6987853)

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAP1A Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB)

Produktdetails anti-RAP1A Antikörper (HRP)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RAP1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RAP1A

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Andere Bezeichnung: RAP1A

Hintergrund:

Synonyms: C21KG, RAP1, G 22K, G-22K, GTP binding protein smg p21A, GTP-binding protein smg p21A, KREV 1, KREV-1, KREV1, OTTHUMP00000013741, RAP 1A, RAP1, RAP1A, RAP1A member of RAS oncogene family, RAP1A_HUMAN, Ras related protein Krev 1, Ras related protein Rap 1A, RAS related protein RAP1A, Ras-related protein Krev-1, Ras-related protein Rap-1A, SMGP21, rap1a, RAS-related protein-1a precursor, Rap1A-retro2, RAP1A, member of RAS oncogene family.

Background: Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.

Gen-ID: 5906

UniProt: P62834

Pathways: T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor