SYNE1 Antikörper (AA 51-150) (HRP)

Produktnummer ABIN6987627

Dieses Anti-SYNE1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SYNE1 in ELISA, IHC (fro) und IHC (p). Geeignet für Ratte.

Kurzübersicht für SYNE1 Antikörper (AA 51-150) (HRP) (ABIN6987627)

Target: SYNE1 (Spectrin Repeat Containing, Nuclear Envelope 1 (SYNE1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNE1 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SYNE1 Antikörper (HRP)

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Nesprin 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SYNE1

Target: SYNE1 (Spectrin Repeat Containing, Nuclear Envelope 1 (SYNE1))

Andere Bezeichnung: Nesprin 1

Hintergrund:

Synonyms: CPG2, Enaptin, Myne-1, MYNE1, Myocyte nuclear envelope protein 1, Nesprin-1, Nuclear envelope spectrin repeat protein 1, SCAR8, Synaptic nuclear envelope protein 1, Syne-1, SYNE1, SYNE1_HUMAN, SYNE1B.

Background: Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Involved in the maintenance of nuclear organization and structural integrity. Connects nuclei to the cytoskeleton by interacting with the nuclear envelope and with F-actin in the cytoplasm. Required for centrosome migration to the apical cell surface during early ciliogenesis.

Gen-ID: 23345

UniProt: Q8NF91

Pathways: Maintenance of Protein Location