YWHAB/YWHAZ Antikörper (pSer184, pSer186) (HRP)

Produktnummer ABIN6987521

Der Kaninchen Polyklonal Anti-YWHAB/YWHAZ-Antikörper wurde für WB, ELISA, IHC (fro) und IHC (p) validiert. Er ist geeignet, YWHAB/YWHAZ in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für YWHAB/YWHAZ Antikörper (pSer184, pSer186) (HRP) (ABIN6987521)

Target: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YWHAB/YWHAZ Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-YWHAB/YWHAZ Antikörper (HRP)

Bindungsspezifität: pSer184, pSer186

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human 14-3-3 beta + zeta around the phosphorylation site of Ser186 / Ser184

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu YWHAB/YWHAZ

Target: YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))

Andere Bezeichnung: 14-3-3 beta + zeta

Hintergrund:

Synonyms: 14-3-3 beta + zeta (phospho S184 + S186), 14-3-3 beta + zeta (phospho S186), 14-3-3 beta + zeta (phospho Ser186), p-14-3-3 beta + zeta (Ser186) 14 3 3 protein beta, 14 3 3 protein beta/alpha, 14 3 3 protein zeta/delta, 14 3 3 zeta, HS1, KCIP1, YWHAB, YWHAZ.

Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

Gen-ID: 7529

UniProt: P31946