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RNF111 Antikörper (AA 851-950) (HRP)

This anti-RNF111 antibody (ABIN6987502) is a Rabbit Polyclonal antibody detecting RNF111 in ELISA, IHC (p), IHC (fro). Suitable for Mouse, Rat.
Produktnummer ABIN6987502

Quick Overview for RNF111 Antikörper (AA 851-950) (HRP) (ABIN6987502)

Target

Alle RNF111 Antikörper anzeigen
RNF111 (Ring Finger Protein 111 (RNF111))

Reaktivität

  • 35
  • 32
  • 22
Maus, Ratte

Wirt

  • 45
  • 4
Kaninchen

Klonalität

  • 47
  • 2
Polyklonal

Konjugat

  • 18
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RNF111 Antikörper ist konjugiert mit HRP

Applikation

  • 21
  • 18
  • 13
  • 13
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 851-950

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Human,Dog,Cow,Sheep,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human RNF111

    Isotyp

    IgG
  • Applikationshinweise

    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    RNF111 (Ring Finger Protein 111 (RNF111))

    Andere Bezeichnung

    RNF111

    Hintergrund

    Synonyms: ARK, Arkadia, DKFZp313E0731, DKFZp686H1966, DKFZp761D081, E3 ubiquitin protein ligase Arkadia, FLJ38008, Ring finger protein 111, RNF 111, RN111_HUMAN.

    Background: The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

    Gen-ID

    54778

    UniProt

    Q6ZNA4
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