MCFD2 Antikörper (AA 1-100) (FITC)

Produktnummer ABIN6987360

Dieses Anti-MCFD2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MCFD2 in WB, IF (cc) und IF (p). Geeignet für Ratte und Maus.

Kurzübersicht für MCFD2 Antikörper (AA 1-100) (FITC) (ABIN6987360)

Target: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCFD2 Antikörper ist konjugiert mit FITC

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MCFD2 Antikörper (FITC)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse MCFD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MCFD2

Target: MCFD2 (Multiple Coagulation Factor Deficiency 2 (MCFD2))

Andere Bezeichnung: MCFD2

Hintergrund:

Synonyms: 1810021C21Rik, DKFZp686G21263, F5F8D, LMAN1IP, MCFD 2, Mcfd2, MCFD2_MOUSE, Multiple coagulation factor deficiency protein 2, Neural stem cell derived neuronal survival protein, Neural stem cell-derived neuronal survival protein, SDNSF.

Background: This gene encodes a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1, also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D), a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jun 2010]

Gen-ID: 193813

UniProt: Q8K5B2