SMAD2 / SMAD3 (pThr8) Antikörper (Cy5)

Produktnummer ABIN6984834

Produktdetails

Target: SMAD2 / SMAD3

Bindungsspezifität: pThr8

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Cy5

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human Smad2/Smad3 around the phosphorylation site of Thr8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: SMAD2 / SMAD3

Andere Bezeichnung: Smad2/Smad3

Hintergrund:

Synonyms: Smad2 + Smad3 (phospho T8), p-Smad2 + Smad3 (phospho T8), P-Smad2 /3 (phospho T8), hMAD 2, hMAD 3, hSMAD2, hSMAD3, Mad related protein 2, MADH2, MADH3, MADR2, Mothers against DPP homolog 2, Mothers against DPP homolog 3, Sma and Mad related protein 2, SMA and MAD related protein 3, SMAD 2, SMAD 3, SMAD family member 2, SMAD family member 3.

Background: SMAD is a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. They mediate the signal of the transforming growth factor (TGF)-beta, and thus regulate multiple cellular processes, such as cell proliferation, apoptosis, and differentiation.

Gen-ID: 4087

UniProt: P84022