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MED12 Antikörper (AA 251-350) (Cy5)

This anti-MED12 antibody (ABIN6984433) is a Rabbit Polyclonal antibody detecting MED12 in WB, IF (cc), IF (p). Suitable for Mouse, Rat.
Produktnummer ABIN6984433

Quick Overview for MED12 Antikörper (AA 251-350) (Cy5) (ABIN6984433)

Target

Alle MED12 Antikörper anzeigen
MED12 (Mediator Complex Subunit 12 (MED12))

Reaktivität

  • 28
  • 25
  • 16
  • 1
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 39
  • 1
  • 1
Kaninchen

Klonalität

  • 40
  • 1
Polyklonal

Konjugat

  • 18
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MED12 Antikörper ist konjugiert mit Cy5

Applikation

  • 25
  • 16
  • 12
  • 12
  • 8
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Human,Cow,Sheep,Pig,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human MED12/Trap230

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    MED12 (Mediator Complex Subunit 12 (MED12))

    Andere Bezeichnung

    MED12/Trap230

    Hintergrund

    Synonyms: Mediator of RNA polymerase II transcription subunit 12, MED12, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45 Mediator complex subunit 12, OPA-containing protein, Thyroid hormone receptor-associated protein complex 230 kDa component, Trap230, Trinucleotide repeat-containing gene 11 protein, MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230

    Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

    Gen-ID

    9968

    UniProt

    Q93074

    Pathways

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Tube Formation
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