PIEZO1 + PIEZO2 (AA 2451-2521) Antikörper (Cy5)

Produktnummer ABIN6984236

Produktdetails

Target: PIEZO1 + PIEZO2

Bindungsspezifität: AA 2451-2521

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Cy5

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus

Homologie: Human,Rat,Dog,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PIEZO1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: PIEZO1 + PIEZO2

Hintergrund:

Synonyms: Piezo-type mechanosensitive ion channel component 1, Piezo-type mechanosensitive ion channel component 2, PIEZO1, PIEZO2, Mib, C18orf30, C18orf58, FAM38B, FAM38A, KIAA0233

Background: Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. 'Piezo' comes from the Greek 'piesi,' meaning 'pressure.' The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types. PIEZO2 Component of a mechanosensitive channel required for rapidly adapting mechanically activated (MA) currents. Required for Merkel-cell mechanotransduction. Plays a major role in light-touch mechanosensation

Gen-ID: 9780

UniProt: Q92508