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IMPACT Antikörper (AA 21-120) (Cy3)

IMPACT Reaktivität: Maus, Ratte WB, IF (cc), IF (p) Wirt: Kaninchen Polyclonal Cy3
Produktnummer ABIN6983412
  • Target Alle IMPACT Antikörper anzeigen
    IMPACT (Impact Homolog (IMPACT))
    Bindungsspezifität
    • 14
    • 14
    • 7
    • 6
    • 2
    • 1
    AA 21-120
    Reaktivität
    • 23
    • 15
    • 15
    Maus, Ratte
    Wirt
    • 35
    • 2
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IMPACT Antikörper ist konjugiert mit Cy3
    Applikation
    • 33
    • 20
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IMPACT
    Isotyp
    IgG
    Top Product
    Discover our top product IMPACT Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    IMPACT (Impact Homolog (IMPACT))
    Andere Bezeichnung
    IMPACT (IMPACT Produkte)
    Synonyme
    zgc:103672 antikoerper, Ximpact antikoerper, impact-A antikoerper, RWDD5 antikoerper, impact-a antikoerper, E430016J11Rik antikoerper, impact RWD domain protein antikoerper, impact antikoerper, impact RWD domain protein L homeolog antikoerper, impact, RWD domain protein antikoerper, IMPACT antikoerper, impact antikoerper, EDI_298310 antikoerper, impact.L antikoerper, Impact antikoerper
    Hintergrund

    Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog

    Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).

    Gen-ID
    55364
    UniProt
    Q9P2X3
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