IMPACT Antikörper (AA 21-120) (Cy3)

Produktnummer ABIN6983412

This anti-IMPACT antibody (ABIN6983412) is a Rabbit Polyclonal antibody detecting IMPACT in WB, IF (cc), IF (p). Suitable for Mouse, Rat.

Kurzübersicht für IMPACT Antikörper (AA 21-120) (Cy3) (ABIN6983412)

Target: IMPACT (Impact Homolog (IMPACT))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IMPACT Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-IMPACT Antikörper (Cy3)

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IMPACT

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IMPACT

Target: IMPACT (Impact Homolog (IMPACT))

Andere Bezeichnung: IMPACT

Hintergrund:

Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog

Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).

Gen-ID: 55364

UniProt: Q9P2X3