ADAP2 Antikörper (AA 201-300) (Cy3)

Produktnummer ABIN6983290

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ADAP2 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für ADAP2 Antikörper (AA 201-300) (Cy3) (ABIN6983290)

Target: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAP2 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ADAP2 Antikörper (Cy3)

Bindungsspezifität: AA 201-300

Spezifität: Possible cross-reactivity with ADAP1 (85 % homology with the immunogen sequence, 43 kDa)

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Centaurin alpha 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ADAP2

Target: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Andere Bezeichnung: Centaurin alpha 2

Hintergrund:

Synonyms: ADAP2, ADAP2_HUMAN, Arf-GAP with dual PH domain-containing protein 2, ArfGAP with dual PH domains 2, cent b, Centa 2, CENTA2, Centaurin alpha 2, Centaurin alpha 2 protein, Centaurin beta, Centaurin-alpha-2, Cnt-a2, HSA272195.

Background: The ADP-ribosylation factor (ARF) family of small GTP-binding proteins are involved in vesicular transport regulation and in controlling cytoskeletal organization and cell adhesion. The Centaurin GTPase-activating protein family comprise a subset of ARF regulatory molecules that transduce PI 3-kinase activation into coordinated control of ARF-dependent pathways. This family includes ASAP1, ACAP1, ACAP2, AGAP1, ARAP1, ARAP2, Centaurin a1, Centaurin g3 and the recently discovered Centaurin a2. Expressed in a wide variety of tissues such as fat, heart and skeletal muscle, Centaurin a2 is thought to negatively regulate ARF-mediated actin rearrangement by binding activated PI 3-kinase. Although the exact function of Centaurin a2 is not yet known, its high sequence similarity with Centaurin a1 suggests that it may also act as an ARF6 GTPase.

Gen-ID: 55803

UniProt: Q9NPF8