NKIRAS1 Antikörper (AA 131-192) (Biotin)

Produktnummer ABIN6982889

Der Kaninchen Polyklonal Anti-NKIRAS1-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, NKIRAS1 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für NKIRAS1 Antikörper (AA 131-192) (Biotin) (ABIN6982889)

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NKIRAS1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NKIRAS1 Antikörper (Biotin)

Bindungsspezifität: AA 131-192

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NKIRAS1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu NKIRAS1

Target: NKIRAS1 (NFKB Inhibitor Interacting Ras-Like 1 (NKIRAS1))

Andere Bezeichnung: NKIRAS1

Hintergrund:

Synonyms: 2400004O09Rik, I kappa B interacting Ras like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B Ras 1, Kappa B Ras protein 1, Kappa B-Ras protein 1, KappaB Ras1, KappaB-Ras1, KBRAS 1, KBRAS1, KBRS1_HUMAN, NF kappa B inhibitor interacting Ras like protein 1, NF-kappa-B inhibitor-interacting Ras-like protein 1, NFKB inhibitor interacting Ras like 1, NFKB inhibitor interacting Ras like protein 1, NKIRAS 1, nkiras1.

Background: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.

Gen-ID: 28512

UniProt: Q9NYS0