HUS1 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN6982666

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HUS1 in ELISA, IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für HUS1 Antikörper (AA 51-150) (Biotin) (ABIN6982666)

Target: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HUS1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HUS1 Antikörper (Biotin)

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HUS1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu HUS1

Target: HUS1 (HUS1 Checkpoint Homolog (S. Pombe) (HUS1))

Andere Bezeichnung: HUS1

Hintergrund:

Synonyms: Checkpoint protein HUS1, hHUS1, HUS1 (S. pombe) checkpoint homolog, Hus1, HUS1 checkpoint homolog (S. pombe), HUS1 Checkpoint Protein, HUS1 protein, HUS1+ - like protein, HUS1_HUMAN, Hydroxyurea-sensitive 1, S. pombe, homolog of.

Background: The protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2011]

Gen-ID: 3364

UniProt: O60921