SBNO1 Antikörper (AA 331-430) (Biotin)

Produktnummer ABIN6982639

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SBNO1 in WB, ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SBNO1 Antikörper (AA 331-430) (Biotin) (ABIN6982639)

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SBNO1 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SBNO1 Antikörper (Biotin)

Bindungsspezifität: AA 331-430

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SBNO1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SBNO1

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Andere Bezeichnung: SBNO1

Hintergrund:

Synonyms: FLJ10701, FLJ10833, FLJ16176, Monocyte protein 3, MOP 3, MOP-3, MOP3, Protein strawberry notch homolog 1, SBNO 1, Sbno1, SBNO1_HUMAN, Sno, Sno strawberry notch homolog 1, Strawberry notch homolog 1.

Background: SBNO1 is a 1,392 amino acid protein encoded by the human gene of the same name located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

Gen-ID: 55206

UniProt: A3KN83

Pathways: SARS-CoV-2 Protein Interaktom