WT1 Antikörper (AA 301-400) (AbBy Fluor® 750)
Kurzübersicht für WT1 Antikörper (AA 301-400) (AbBy Fluor® 750) (ABIN6982457)
Target
Alle WT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 301-400
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Kreuzreaktivität
 - Rind (Kuh), Human, Maus, Ratte
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Homologie
 - Dog,Cow,Sheep,Pig,Chicken
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Aufreinigung
 - Purified by Protein A.
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Immunogen
 - KLH conjugated synthetic peptide derived from human Wilms Tumor Protein
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Isotyp
 - IgG
 
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Applikationshinweise
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                        FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 μg/μL
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Buffer
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
 - 12 months
 
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- WT1 (Wilms Tumor 1 (WT1))
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Andere Bezeichnung
 - Wilms Tumor Protein
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Hintergrund
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Synonyms: GUD, AWT1, WAGR, WT33, NPHS4, WIT-2, EWS-WT1, Wilms tumor protein, WT1
Background: Transcription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
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Gen-ID
 - 7490
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UniProt
 - P19544
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Pathways
 - Tube Formation
 
Target
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