MSTN Antikörper (AA 301-375) (AbBy Fluor® 680)

Produktnummer ABIN6981343

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MSTN in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für MSTN Antikörper (AA 301-375) (AbBy Fluor® 680) (ABIN6981343)

Target: MSTN (Myostatin (MSTN))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MSTN Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-MSTN Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 301-375

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Sheep,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GDF8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu MSTN

Target: MSTN (Myostatin (MSTN))

Andere Bezeichnung: GDF8

Hintergrund:

Synonyms: GDF 8, GDF-8, GDF8_HUMAN, Growth differentiation factor 8, Growth/Differentiation Factor 8, MSTN, myostatin, OTTHUMP00000163498.

Background: The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. Acts specifically as a negative regulator of skeletal muscle growth. [SUBUNIT] Homodimer, [TISSUE SPECIFICITY] Expressed specifically in developing and adult skeletal muscle. Weak expression in adipose tissue. Belongs to the TGF-beta family.

Gen-ID: 2660

UniProt: O14793