SBNO1 Antikörper (AA 331-430) (AbBy Fluor® 647)

Produktnummer ABIN6980034

Dieses Anti-SBNO1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SBNO1 in WB, IF (cc) und IF (p). Geeignet für Human.

Kurzübersicht für SBNO1 Antikörper (AA 331-430) (AbBy Fluor® 647) (ABIN6980034)

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SBNO1 Antikörper ist konjugiert mit AbBy Fluor® 647

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SBNO1 Antikörper (AbBy Fluor® 647)

Bindungsspezifität: AA 331-430

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SBNO1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SBNO1

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Andere Bezeichnung: SBNO1

Hintergrund:

Synonyms: FLJ10701, FLJ10833, FLJ16176, Monocyte protein 3, MOP 3, MOP-3, MOP3, Protein strawberry notch homolog 1, SBNO 1, Sbno1, SBNO1_HUMAN, Sno, Sno strawberry notch homolog 1, Strawberry notch homolog 1.

Background: SBNO1 is a 1,392 amino acid protein encoded by the human gene of the same name located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

Gen-ID: 55206

UniProt: A3KN83

Pathways: SARS-CoV-2 Protein Interaktom