STAR Antikörper (AA 181-285) (AbBy Fluor® 594)
Kurzübersicht für STAR Antikörper (AA 181-285) (AbBy Fluor® 594) (ABIN6979432)
Target
Alle STAR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 181-285
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Pig,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human StAR
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- STAR (Steroidogenic Acute Regulatory Protein (STAR))
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Andere Bezeichnung
- StAR
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Hintergrund
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Synonyms: StARD1, Cholesterol trafficker, Luteinizing hormone induced protein, Mitochondrial steroid acute regulatory protein, StAR related lipid transfer (START) domain containing 1, StARD1, START domain containing protein 1, Steroidogenic Acute Regulatory Protein, Steroidogenic acute regulatory protein mitochondrial, STAR_HUMAN.
Background: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008].
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Gen-ID
- 6770
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UniProt
- P49675
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis
Target
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